西那西呱

{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 444574102
| IUPAC_name = 4-({(4-carboxybutyl)[2-(2-{[4-(2-phenylethyl)
phenyl]methoxy}phenyl)ethyl]amino}methyl)
benzoic acid
| image = Cinaciguat_structure.svg

| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration = 静脉注射 (?)

| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =

| IUPHAR_ligand = 5168
| CAS_number_Ref =
| CAS_number = 329773-35-5
| CAS_supplemental =
| ATC_prefix = none
| ATC_suffix =
| ATC_supplemental =
| ChEBI = 142433
| PubChem = 9808022
| DrugBank_Ref =
| DrugBank =
| UNII_Ref =
| UNII = 59K0Y58UAD
| ChemSpiderID_Ref =
| ChemSpiderID = 7983781
| StdInChI_Ref =
| StdInChI = 1S/C36H39NO5/c38-35(39)12-6-7-24-37(26-30-19-21-33(22-20-30)36(40)41)25-23-32-10-4-5-11-34(32)42-27-31-17-15-29(16-18-31)14-13-28-8-2-1-3-9-28/h1-5,8-11,15-22H,6-7,12-14,23-27H2,(H,38,39)(H,40,41)
| StdInChIKey_Ref =
| StdInChIKey = WPYWMXNXEZFMAK-UHFFFAOYSA-N

| chemical_formula =
| C=36 | H=39 | N=1 | O=5
| smiles = c4ccccc4CCc3ccc(cc3)COc1ccccc1CCN(CCCCC(O)=O)Cc2ccc(C(=O)O)cc2
}}

西那西呱（INN：cinaciguat；开发代号：BAY 58-2667）是一种实验性激活剂，设计用于治疗。该药物能提高环磷酸鸟苷的产量进而引起肺血管舒张。

参考资料