瑞普特罗

{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 448131419
| IUPAC_name = (RS)-7-(3-{[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino}propyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
| image = (RS)-Reproterol Structural Formula V1.svg
| width = 250

| tradename =
| Drugs.com =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_DE = Rx only
| legal_status =
| routes_of_administration = 吸入（、静脉注射

| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =

| CAS_number_Ref =
| CAS_number = 54063-54-6
| ATC_prefix = R03
| ATC_suffix = AC15
| ATC_supplemental =
| PubChem = 25654
| DrugBank_Ref =
| DrugBank =
| ChEMBL_Ref =
| ChEMBL = 1095607
| UNII_Ref =
| UNII = 11941YC6RN
| KEGG_Ref =
| KEGG = D08474
| ChemSpiderID_Ref =
| ChemSpiderID = 23898

| chemical_formula =
| C=18 | H=23 | N=5 | O=5
| smiles = CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCCNCC(C3=CC(=CC(=C3)O)O)O
| StdInChI_Ref =
| StdInChI = 1S/C18H23N5O5/c1-21-16-15(17(27)22(2)18(21)28)23(10-20-16)5-3-4-19-9-14(26)11-6-12(24)8-13(25)7-11/h6-8,10,14,19,24-26H,3-5,9H2,1-2H3
| StdInChIKey_Ref =
| StdInChIKey = WVLAAKXASPCBGT-UHFFFAOYSA-N
}}

瑞普特罗（INN：reproterol）是一种短效β2肾上腺素受体激动剂，用于治疗哮喘。

它于1965年获得专利，并于1977年进入医疗用途。

立体化学
瑞普特罗含有立体中心并且是手性的。因此存在两种对映体：(R)-形式和(S)-形式。商业制剂含有药物的外消旋体，即两种对映体的等量混合物。

参考资料