卡布特罗

{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 443941802
| IUPAC_name = (RS)-{5-[2-(tert-butylamino)-1-hydroxyethyl]-2-hydroxyphenyl}urea
| image = Carbuterol.svg
| width = 230
| chirality = 外消旋混合物

| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU = S4
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref =
| CAS_number = 34866-47-2
| ATC_prefix = R03
| ATC_suffix = CC10
| ATC_supplemental =
| ChEMBL_Ref =
| ChEMBL = 2110780
| PubChem = 36976
| DrugBank_Ref =
| DrugBank =
| ChemSpiderID_Ref =
| ChemSpiderID = 33928
| UNII_Ref =
| UNII = 0N12JR32MR

| C = 13
| H = 21
| N = 3
| O = 3
| smiles = O=C(Nc1cc(ccc1O)C(O)CNC(C)(C)C)N
| StdInChI_Ref =
| StdInChI = 1S/C13H21N3O3/c1-13(2,3)15-7-11(18)8-4-5-10(17)9(6-8)16-12(14)19/h4-6,11,15,17-18H,7H2,1-3H3,(H3,14,16,19)
| StdInChIKey_Ref =
| StdInChIKey = KEMXXQOFIRIICG-UHFFFAOYSA-N
}}

卡布特罗（INN：carbuterol）是一种短效β2肾上腺素受体激动药、支气管扩张药。卡布特罗在猫、狗和豚鼠的体外和体内表现出有效的支气管扩张活性，并且与异丙肾上腺素相比，卡布特罗对气管支气管平滑肌的选择性比对心肌的选择性高得多。

合成
参考资料