坦索羅辛

{{Drugbox
| Watchedfields = changed
| verifiedrevid = 461746753
| IUPAC_name = (R)-5-(2-{[2-(2-Ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzene-1-sulfonamide
| image = Tamsulosin Structural Formulae.png
| width = 250
| image2 = Tamsulosin ball-and-stick.png

| tradename = Flomax, others
| Drugs.com =
| pronounce =
| MedlinePlus = a698012
| licence_US = Tamsulosin
| pregnancy_AU = B2
| pregnancy_US = B
| legal_AU = S4
| legal_UK = POM
| legal_US = Rx-only
| routes_of_administration = 口服

| bioavailability = 100%（口服）
| metabolism = 肝
| elimination_half-life = 9–13小時
| excretion = 76% 腎

| CAS_number_Ref =
| CAS_number = 106133-20-4
| ATC_prefix = G04
| ATC_suffix = CA02
| PubChem = 129211
| IUPHAR_ligand = 488
| DrugBank_Ref =
| DrugBank = DB00706
| ChemSpiderID_Ref =
| ChemSpiderID = 114457
| UNII_Ref =
| UNII = G3P28OML5I
| KEGG_Ref =
| KEGG = D08560
| ChEBI_Ref =
| ChEBI = 9398
| ChEMBL_Ref =
| ChEMBL = 836

| C=20 | H=28 | N=2 | O=5 | S=1
| molecular_weight = 408.51
| smiles = CCOc1ccccc1OCCNC@@HCc1ccc(OC)c(c1)S(=O)(=O)N
| StdInChI_Ref =
| StdInChI = 1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1
| StdInChIKey_Ref =
| StdInChIKey = DRHKJLXJIQTDTD-OAHLLOKOSA-N
}}

坦索羅辛（INN：tamsulosin）商品名有 Flomax，Harnalidge，是选择性α1受体拮抗剂，使尿路平滑肌松弛，可以治療有症狀的良性前列腺肥大症（BPH）、慢性前列腺炎/慢性骨盆疼痛綜合症，也可以幫助腎結石排出。目前的證據顯示對較大的腎結石效果較好；藉此使尿路（包括：膀胱颈、前列腺、输尿管、尿道）平滑肌松弛以達療效。

美國在1997年核可坦索羅辛的醫療使用，而同年在英國國民保健署每劑採購價為0.04英磅。2016年時此藥物是全美國最常被處方藥物排名中的第32名，一年的處方量超過2,200萬劑。

參考資料
外部連結

• [https://web.archive.org/web/20061016204638/http://www.drugs.com/pdr/flomax_capsules.html Flomax (drugs.com)] – U.S. product information
• [http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020579s025lbl.pdf Product label] U.S. Food and Drug Administration (FDA)
• [https://www.nlm.nih.gov/medlineplus/druginfo/meds/a698012.html Tamsulosin] – information from USP DI Advice for the Patient