α1-B-糖蛋白()是一种功能未知的血浆糖蛋白,分子量为54.3 kDa,由A1BG 基因编码,和免疫球蛋白超家族成员的可变区序列有着一定相似性。胰管腺癌患者的胰液中会出现A1BG过表达。
同源体
直系同源
如下表所示,α-1-B糖蛋白在如下动物中都是保守的,很可能在所有哺乳动物中都具有一定的保守性。
旁系同源
目前并未发现α-1-B糖蛋白的旁系同源体。
同源结构域
An initial NCBI Blast alignment of alpha-1B glycoprotein illustrates that the protein is mainly composed of three immunoglobulin domains.There is a large segment of amino acids from position 297 to 400 that is not shown to be an immunoglobulin domain. However, a NCBI BLAST alignment of just the amino acids from 297-400 does illustrate that the latter sequence is indeed a fourth immunoglobulin domain.Ultimately, alpha-1B glycoprotein seems to be primarily composed of four immunoglobulin domains.
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