金刚乙胺()是一种抗病毒药,属于三环胺类,对A型流感病毒有预防和治疗作用,且作用强于金刚烷胺。金刚乙胺的中枢神经副作小于金刚烷胺。金刚乙胺通过抑制特异蛋白的释放,而干扰病毒脱壳,它能抑制逆转录酶而发挥抗病毒活性或抑制病毒特异性RNA的合成,但却不影响病毒的吸附和穿入。金刚乙胺在肾排泄前被代谢。
相关药物
*金刚烷胺
外部連結
- [http://www.fda.gov/bbs/topics/ANSWERS/ANS00530.html U.S. FDA press release announcing rimantadine's approval]
- [https://web.archive.org/web/20050630080607/http://www.fda.gov/cder/drug/antivirals/influenza/flumadine.htm U.S. Center for Drug Evaluation and Research rimantadine description]
- [http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a698029.html U.S. NIH rimantadine description]
- [http://www.cdc.gov/flu/professionals/treatment/index.htm U.S. CDC flu anti-viral treatment information]
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